Eliana sosco biography of alberta
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Characteristics of genomic signatures derived using univariate methods and mechanistically anchored functional descriptors for predicting drug- and xenobiotic-induced nephrotoxicity.
PubMed
Shi, Weiwei; Bugrim, Andrej; Nikolsky, Yuri; Nikolskya, Tatiana; Brennan, Richard J
2008-01-01
ABSTRACT The ideal toxicity biomarker is composed of the properties of prediction (is detected prior to traditional pathological signs of injury), accuracy (high sensitivity and specificity), and mechanistic relationships to the endpoint measured (biological relevance). Gene expression-based toxicity biomarkers ("signatures") have shown good predictive power and accuracy, but are difficult to interpret biologically. We have compared different statistical methods of feature selection with knowledge-based approaches, using GeneGo's database of canonical pathway maps, to generate gene sets for the classification of renal tubule toxicity. The gene set selection algorithms include four univariate analys
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Vol. 9 No. 4 Winter 2011
Vol.9 No.4WINTER 2011 $4.95 Canada brev Publication Agreement number 40671108
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MANUFACTURING CLOSE-UP LONGBOARDING IN PARIS WHEEL SECRETS
Vol.9 No.4WINTER 2011 $4.95 MANUFACTURING CLOSE-UP LONGBOARDING
PARIS
IN
WHEEL SECRETS REVEALED
12 CONCRETE WAVE WINTER 2011 CONCRETEWAVEMAGAZINE.COM VANCOUVER’S “LADIES OF DOWNHILL”: A TRIBUTE TO GLENNA EVANS 50 MANUFACTURING CLOSE UP PART 1 62 CONTENTS >> DEPARTMENTS In last issue of Concrete Wave, Aaron Enevoldsen de---elated disbelief after an hour of fast,--Ouarzazate to Fez LEG4 22 EDITORIAL 26 LETTERS 28 NOTEWORTHY 38 THE SILVERFISH REPORT 40 RIDER PROFILE: LAURA ALLI 42 TECH TALK: WHEEL SECRETS REVEALED 44 FROM THE FRIDGE TO HOT SAUCE 46 ASK BIKER 48 KING SOLOMON’S RULES 86 IGSA REPORT 54 LONGBOARDING IN PARIS ANOTHER LOOK AT HELMETS 74 THE MOROCCAN SKATE PARADE 82 Verne Troyer. Photo: ©Scott Harrison/Corbis The City of Love is Ripe for Push Culture Safety First… Drama Second! Part 2 Taking Yo
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The effects of Global Fund financing on health governance in Brazil
PubMed Central
2012-01-01
Objectives The impact of donors, such as national government (bi-lateral), private sector, and individual financial (philanthropic) contributions, on domestic healthpolicies of developing nations has been the subject of scholarly discourse. Little is known, however, about the impact of global financial initiatives, such as the Global Fund to Fight AIDS, Tuberculosis, and Malaria, on policies and health governance of countries receiving funding from such initiatives. Methods This study employs a qualitative methodological design based on a single case study: Brazil. Analysis at national, inter-governmental and community levels is based on in-depth interviews with the Global Fund and the Brazilian Ministry of Health and civil societal activists. Primary research is complemented with information from printed media, reports, journal articles, and books, which were used to deepen our analysi